Oxford United are on the road to play at St Mary's for the first time, with Southampton the hosts in this Championship fixture.
It's the first away game since the fantastic 3-1 win over Preston North End at Deepdale, hoping to continue some impressive recent away form.
Matt Bloomfield has made two changes to the line-up from the draw with Charlton Athletic, with Brodie Spencer in for Jamie Donley, who drops out to the bench, and Myles Peart-Harris back in for Aidomo Emakhu.
Kick-off in Southampton is at 3:00pm. You can keep up to date with all the action on the Club's Official Instagram and X accounts.
Oxford United: Cumming, Long, Brown, Konak, Helik, Brannagan, Spencer, Mills, Currie, Lankshear, Peart-Harris
Subs: Ingram, Vaulks, Harris, Emakhu, Prelec, Jin Woo, Donley, Makosso, McDonnell
