The U's look to mak it four wins in a row having moved in to the play-off places at the weekend, but face an in form AFC Wimbledon side on unfamiliar territory.
United welcome back Mark Sykes and Brandon Barker after they missed Saturday's dramatic 3-2 win at home to Gillingham, with only Marcus McGuane and John Mousinho unavailable.
Alex Gorrin returned to the bench on Saturday while Sam Winnall scored as a sub and will be pushing for a starting place.
See Sam and Karl Robinson previewing the game in iFollow now.
Four wins from six games have pulled Mark Robinson's side away from the danger zone with a 4-1 win against Swindon, in which they also hit the woodwork three times, the latest in a string of encouraging performances
“Going forward, it was the best we’ve played, no doubt,” the Manager said. “We played so quickly and in varied ways, whether it was quick combinations, one touch stuff, or going in behind. There was a bit of everything going on, as well as some great individual skill as well. That carried on for the beginning of the second-half as well. Going forward we were so exciting, but there were things we still needed to improve upon defensively.
“Obviously, we are happy and you have to celebrate and enjoy your football, but the standards have been set and we are having those discussions. We have to prepare for the next game and take more points and that has to continue right until the end of the season".
It’s a new ground for the U’s tonight. AFC Wimbledon played the first four home matches of the season at Loftus Road whilst their new Plough Lane home was being completed before they played their first match at their new stadium on 3rd November, a 2–2 draw against Doncaster Rovers. The U’s played six times at the original Plough Lane, which is 200 yards away from the new ground. Martin Foyle scored in a 1-1 draw the last time the teams met at that ground, back in 1987.
Match Passes are available HERE to see the full game with live commentary from our friends at BBC Oxford Sport
We have all the build up on twitter and on our official Insta page, complete with behind the scenes exclusive content, plus a full report and Gallery right here on the final whistle and reaction from all the key men in iFollow.